Blar i forfatter "Lofterød, Trygve"

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    • Exploring the effects of lifestyle on breast cancer risk, age at diagnosis, and survival: the EBBA-Life study 

      Lofterød, Trygve; Frydenberg, Hanne; Flote, Vidar Gordon; Eggen, Anne Elise; McTiernan, A; Mortensen, Elin Synnøve; Akslen, Lars A.; Reitan, J. B.; Wilsgaard, Tom; Inger, Thune (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-05-20)
      <i>Purpose</i> - Whether an unfavorable lifestyle not only affects breast cancer risk, but also influences age at onset of breast cancer and survival, is under debate.<br><br> <i>Methods</i> - In a population-based cohort, the Energy Balance and Breast Cancer Aspects throughout life (EBBA-Life) study, a total of 17,145 women were included. During follow-up, 574 women developed invasive breast cancer. ...

    • Gene variations in oestrogen pathways, CYP19A1 , daily 17ß-estradiol and mammographic density phenotypes in premenopausal women. 

      Flote, Vidar Gordon; Furberg, Anne-Sofie; McTiernan, Anne; Frydenberg, Hanne; Ursin, Giske; Iversen, Anita; Lofterød, Trygve; Ellison, Peter T.; Wist, Erik; Egeland, Thore; Wilsgaard, Tom; Makar, Karen W; Chang-Claude, Jenny; Thune, Inger (Journal article; Tidsskriftartikkel; Peer reviewed, 2014-12-19)

    • Impact of pre-diagnostic triglycerides and HDL-cholesterol on breast cancer recurrence and survival by breast cancer subtypes 

      Lofterød, Trygve; Mortensen, Elin Synnøve; Nalwoga, Hawa; Wilsgaard, Tom; Frydenberg, Hanne; Risberg, Terje; Eggen, Anne Elise; McTiernan, Anne; Aziz, Sura Mohammed; Wist, Erik; Stensvold, Andreas; Reitan, Jon Brinchmann; Akslen, Lars A.; Thune, Inger (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-06-15)
      <i>Background</i>: High triglycerides and low levels of high density lipoprotein (HDL)-cholesterol are observed to promote tumor growth. However, whether breast cancer heterogeneity may explain the contradictory influence of triglycerides and cholesterol observed on breast cancer prognosis remains unclear.<p> <p><i>Methods</i>: A population-based survival study among 464 breast cancer cases ...

    • Inflammation of mammary adipose tissue occurs in overweight and obese patients exhibiting early-stage breast cancer 

      Vaysse, Charlotte; Lømo, Jon; Garred, Øystein; Fjeldheim, Frøydis Nyborg; Lofterød, Trygve; Schlichting, Ellen; McTiernan, Anne; Frydenberg, Hanne; Husøy, Anders; Lundgren, Steinar; Fagerland, Morten W; Richardsen, Elin; Wist, Erik; Muller, Catherine; Thune, Inger (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-05-03)
      Growing evidence indicates that adiposity is associated with breast cancer risk and negatively affects breast cancer recurrence and survival, a paracrine role of mammary adipose tissue being very likely in this process. In contrast to other adipose depots, occurrence of a sub-inflammatory state of mammary adipose tissue defined by dying adipocytes surrounded by macrophages forming crown-like structures ...

    • The influence of metabolic factors and ethnicity on breast cancer risk, treatment and survival: The Oslo ethnic breast cancer study 

      Lofterød, Trygve; Frydenberg, Hanne; Veierød, Marit Bragelien; Jenum, Anne Karen; Reitan, Jon Brinchmann; Wist, Erik; Thune, Inger (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-03-29)
      Background - Breast cancer risk remains higher in high-income compared with low-income countries. However, it is unclear to what degree metabolic factors influence breast cancer development in women 30 years after immigration from low- to a high-incidence country.<p> <p>Methods - Using Cox regression models, we studied the association between pre-diagnostic metabolic factors and breast cancer ...